Impaired insulin secretion. Increased insulin resistance. Affected glucose tolerance. Reduced antidiabetic effects of acarbose, acetohexamide, chlorpropamide, glipizide, glyburide, metformin, miglitol, pioglitazone, repaglinide, rosiglitazone, glimepiride, tolbutamide, troglitazone. Reduced effectiveness of doxorubicin, etoposide, teniposide. Potentiated anticoagulant effects of warfarin. Powd for oral soln: Formed complexes w/ chitosan.